Gameplay wise, it would increase the number of interesting cases med gets beyond “Me hurt, you fix.”
Lore wise: Synthflesh replaces damaged skin, if it gets inside you it may corrupt and spread in unforeseen ways. Causing internal issues, from appendicitis to possible brain injury.
I think it could add to the game, what do you think?
Would make a lot of sense, since youd imagine getting some synthflesh into your bloodstream would almost mean skin cancer.
Though the much more needed addition is broken bones, i think. Not only is fixing a bone a little process, its also a big buff to lethals, which would make them more viable. (Breaking a leg of a runaway criminal by shooting it with a slug, for example).